Meldonium is a fatty acid oxidation inhibitor and, today, it is principally used to treat angina and heart attacks (myocardial infarction). Its therapeutic activity is produced by altering pathways for carnitine, a nutrient involved in fat metabolism.3
A study in 2005 found that meldonium, in combination with an angiotensin-converting enzyme inhibitor called lisinopril, improved exercise capability and peripheral circulation for individuals with chronic heart failure.
A Chinese study group then tested meldonium for its efficacy in treating acute ischemic stroke, finding it as useful as cinepazide, a vasodilator commonly used to treat acute cerebral infarction.
Other uses for meldonium include:
- Immune system modulation
- Treating stomach ulcers
- Treating eye trauma
- Treating infections of the lungs and upper respiratory tract.